HIV Infection

Roadblock:

The HIV epidemic is taking an enormous toll in the lives of millions of people, particularly in the developing world. Efficient methods of preventing transmission, infection, and the effects of the virus have remained elusive. Cellular or antibody-based approaches for traditional HIV vaccines have not yet yielded measures of efficacy for either prevention or therapy.

Roadblock:

NIH/NIAID Collaboration with Gates Foundation

Roadblock:

While antiretroviral drugs have been successful in expanding treatment to patients worldwide, current therapies do not clear the infection and so require life-long treatment to prevent the infection from progressing to more advanced forms of disease. The costs, scaling and maintenance of this treatment for the growing affected population are daunting. New methods need to be discovered that can permanently eliminate infection, even in cases where effects of the virus are being controlled with current drugs.

Roadblock:

The HIV epidemic is taking an enormous toll in the lives of millions of people, particularly in the developing world. Efficient methods of preventing transmission, infection, and the effects of the virus have remained elusive. Cellular or antibody-based approaches for traditional HIV vaccines have not yet yielded measures of efficacy for either prevention or therapy.