Paul Kim of Johns Hopkins University in the U.S. will modify HIV by removing the viral genome and replacing the outer domain of the gp120 protein, used by the virus to invade host immune cells, with receptors normally used by gp120 to bind to host cells. When this modified ghost virus encounters native HIV during an infection, hidden epitopes are exposed to the host immune system, stimulating antibodies to clear the infection.
Grant ID
OPP1006979
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Follow-on Funding
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Funding Amount (in original currency)
100000.00
Funding Currency
USD
Funding Amount (in USD)
100000.00
Project Type
Project Primary Sector
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Funding Date Range
-
Funding Total (In US dollars)
100000.00
Co-Funded
False