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Novel Delivery of Protein Anthelmintics

Raffi Aroian of the University of California, San Diego in the U.S. proposes to develop a delivery system for non-toxic, anti-roundworm proteins. With this system, mass production of a safe, potent cure for intestinal Roundworms that is cheap and compatible with global distribution should be possible. This project's Phase I research demonstrated that an anthelmintic protein could be expressed in three food-grade bacterial strains safe for humans. The aim of the Phase II project is to optimize the therapeutic activity and production of this protein in several food-grade bacteria to provide a cure for hookworms and other soil-transmitted helminths that is highly effective, inexpensive, capable of being produced on a large scale, and deliverable in many forms compatible with local customs.

Grant ID
OPP1025524
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On
Show on Spoke
On
Follow-on Funding
On
Lead Funding Organization
Principal Investigator
Individual Funder Information
Funding Organization
Funding Amount (in original currency)
100000.00
Funding Currency
USD
Funding Amount (in USD)
100000.00
Project Type
Project Primary Sector
Funding Date Range
-
Funding Total (In US dollars)
100000.00
Co-Funded
False