Combinatorial Vaccine to Protect Women Against Disease

Ali Salanti of the University of Copenhagen in Denmark will develop and test a vaccine combining a new placental malaria vaccine candidate with the cervical cancer vaccine, with the potential of inducing a strong protective response against both diseases simultaneously. This project's Phase I research demonstrated that a combinatorial HPV and placental malaria vaccine induced highly functioning antibodies relevant to both diseases. In Phase II Salanti will further optimize the immune response to the combinatorial vaccine and investigate the scalability and efficient production of such a vaccine for the developing world.