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Novel Antigen Design and Delivery for Mucosal Protection Against HIV-1 Infection

Dr. Shattock and collaborators in the U.K. and South Africa will attempt to develop an HIV vaccine that stimulates immunity to the virus in the lining of the vagina. The investigators hypothesize that an HIV vaccine will be most effective at the site where the virus enters the body. Innovative combinations of vaccine antigen formulas and delivery technologies will be used to develop a potentially potent and effective vaccine. The vaccine will be designed to be delivered via low-cost vaginal gels or via silicone rings that fit inside the vagina and can be self-administered.

Grant ID
OPP37872
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Funding Amount (in original currency)
19700000.00
Funding Currency
USD
Funding Amount (in USD)
19700000.00
Project Primary Sector
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Funding Date Range
-
Funding Total (In US dollars)
19700000.00
Co-Funded
False