Therapeutics/Drugs

Dr. Jiang's team is identifying components of human cells that microbes use to establish an infection and replicate but that are not essential to the human host. Better understanding of microbial replication and survival from the view of host cells, the project team anticipates, will provide a foundation for novel therapeutic approaches to combat infectious diseases while simultaneously providing a low likelihood of inducing drug resistance. These compounds could potentially work by interrupting microbes from creating the environment they need to replicate in human cells.

Brain infections, like malaria, can impair brain function such as memory, thinking, reasoning and speech. Young children who survived severe malaria, some of whom obtained rapid treatment with a new, effective drug, will be traced and assessed for brain function. Proof that treatment reduces disability, will expedite policy changes to prevent malaria and increase treatment access.

Reducing Maternal Mortality and Vertical HIV Transmission: The Saving Mothers and Babies Project - Mara Region, Tanzania

An international group of public and private organizations is collaborating to accelerate development of an innovative heat-stable and low-cost, inhaled form of oxytocin to manage postpartum hemorrhage in resource-poor settings. The technology, originally developed at the Monash Institute of Pharmaceutical Sciences, is being licensed to GSK as part of a collaborative agreement to co-develop, register and distribute the product in regions of high maternal mortality.

Our project will be implemented by scientists in Tanzania. Anaemia is a global public health problem, affecting all individuals; especial young children and pregnant women. The project will evaluate the effectiveness of Rosella flower products in correcting iron deficiency anaemia in human. It intends to provide best and cheaper alternative treatment to anaemia which will solve issues related to present treatment. Follow Emanuel Peter on Twitter @EmanuelPeter5"

More than one-third of the global population (2.8 billion people) suffers from tooth decay and cavities in permanent teeth, with a large increase being recorded in developing countries. This project aims to destroy bacteria responsible for dental caries with a combination of synthetic human antibodies and antibodies from edible plants.

Effect of L-type calcium channel blockers (Amlodipine) on myocardial iron deposition in thalassemic patients with moderate to severe myocardial iron deposition: A Randomized Control Trial.

Traditional Healers, the oxen of the land!

Our project, ""Defeating the Giant with a slingshot: Testing a new technology to fight the global trauma epidemic,"will be carried out in collaboration between the Douglas Mental Health University Institute (Montreal, Canada) and the non-governmental organization Center for Victims of Torture (Kathmandu, Nepal). Currently, there exists no inexpensive and culturally appropriate treatment for people suffering from post traumatic stress disorder (PTSD) in low- and middle-income countries.

The study will investigate the chemical composition of the different Kenyan opuntia plant varieties and demonstrate that the plants possess anti-diabetic properties. The study also seeks to demonstrate that the chemical compounds are absorbed by the camel following an opuntia diet supplement and excreted through camel milk.