Community and Hospital Acquired Invasive Carbepenem Resistant Enterobacteriaceae: Longitudinal Study of the Gut Microbiome in Infected and Non-Infected Children and Their Families

The study plans to collect stool samples from children admitted to the ICU to identify invasive MDR Enterobacteriaceae. Serial sampling of these children and subsequently their family members in the community will allow for longitudinal study of the microbiome and the presence of carbapenemase bacterial genes in their faecal samples. This will allow assessment of the risk of secondary transmission of hospital acquired resistant strains to household contacts