Engineered H. pylori as a Diarrheal Vaccine Platform

Martin Blaser of the New York University School of Medicine in the U.S. proposes to engineer a harmless modification of H. pylori, a bacteria commonly found in the human stomach, to deliver antigens to protect against intestinal pathogens such as cholera and campylobacter. This modified H. pylori can only survive in the presence of an enzyme supplied in special drinking water, allowing those administering the vaccine to regulate its colonization.