Hivi: A Novel Weapon to Kill HIV

Chang Liu and Xiaohong Kong of Nankai University in China seek to develop a self-destructive virus vector called HIVi, which will express small interfering RNA to silence HIV in infected cells, and also replicate in a controlled manner to outcompete the HIV infection before turning itself off. The efficacy of HIVi in interfering with HIV will be assessed using a number of standard HIV cell-based assays.