Increased Stability and Immunogenicity of Bacterial Vaccines

Frank Robb of the University of Maryland, Baltimore in the U.S. will genetically integrate heat shock proteins from thermopilic organisms, which thrive at relatively high temperatures, into attenuated bacterial vaccines to try to enhance the viability and immunogenicity of these vaccines during the freeze-drying process. If successful, this method could enhance the delivery of low -cost, highly-effective vaccines without the need for refrigeration.