Federica Marelli-Berg of Imperial College London in the United Kingdom will test the theory that using "homing factors" as vaccine adjuvants will induce the development of memory T cells, thereby generating site-specific immunity against pathogens in the gut. This project's Phase I research demonstrated that helminth infection in the presence of a homing factor led to an enhanced immunological effect. In Phase II, Marelli-Berg, now at the Queen Mary University of London, aims to develop this observation into a vaccination protocol for clinical application in this and other infections.
Grant ID
OPP1008115
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Funding Amount (in original currency)
100000.00
Funding Currency
USD
Funding Amount (in USD)
100000.00
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Funding Date Range
-
Funding Total (In US dollars)
100000.00
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False