Sublingual Vaccination for Inducing Broad-Based Mucosal Immunity

Cecil Czerkinsky of the International Vaccine Institute in South Korea will test the efficacy of administering two approved vaccines sublingually - directly under the tongue. The team will attempt to produce not only antibody responses but also cytotoxic T cell responses in distant mucosal organs such as the lungs and reproductive tract. Sublingual vaccine administration could help improve vaccine delivery, compliance, and enhance immunity against a variety of pathogens.