Noncommunicable Diseases

Our project will be implemented by scientists in Tanzania. Anaemia is a global public health problem, affecting all individuals; especial young children and pregnant women. The project will evaluate the effectiveness of Rosella flower products in correcting iron deficiency anaemia in human. It intends to provide best and cheaper alternative treatment to anaemia which will solve issues related to present treatment. Follow Emanuel Peter on Twitter @EmanuelPeter5"

We are developing a programmatic approach to empower community health workers in the developing world with a simple-to-use, needle-free, hand-held, anemia screening device (""ToucHb""), with the goal of improving maternal and child health outcomes. Follow Biosense Technologies on Twitter @BiosenseToucHB"

About one-third of India’s population is prone to chronic renal disease. Screening the population can be done by measuring micro-albumin levels in urine but existing methods are costly. This project presents an indigenous, low-cost micro-albumin to creatinine urine dipsticks with a screening mat integrated to a mobile device.

Hydrocephalus (excessive fluid in the brain) afflicts over 14,000 infants annually in East, Central and Southern Africa. Left untreated, it can halt development and is often fatal in the first years of life. However it is treatable, but the treatments are surgical, which is difficult to access due to lack of equipment and trained personnel. This results in less than 10% of affected children receiving treatment in these regions. Endoscopic treatment of hydrocephalus is advocated in low-resource areas because it can cure up to 70% of cases without lifelong dependence on an external drain.

More than one-third of the global population (2.8 billion people) suffers from tooth decay and cavities in permanent teeth, with a large increase being recorded in developing countries. This project aims to destroy bacteria responsible for dental caries with a combination of synthetic human antibodies and antibodies from edible plants.

Effect of L-type calcium channel blockers (Amlodipine) on myocardial iron deposition in thalassemic patients with moderate to severe myocardial iron deposition: A Randomized Control Trial.

Acute kidney injury (AKI) is caused by other conditions such as malaria, HIV-related infection, diarrheal disease or pregnancy-related complications. It is a neglected global health issue and a significant cause of illness and death in low-income countries, particularly in sub-Saharan Africa, where access to early diagnosis and timely access to therapy are lacking. This project will develop and test a system that uses a smartphone biosensor and two drops of blood to rapidly measure kidney failure in any setting for less than $1.

In developing countries, kidney disease often progresses to kidney failure because of late diagnosis. A new test (eGFR) can identify this disease at an earlier stage. We will standardize creatinine measurements and introduce eGFR reporting to Guyana.

An estimated 2% of deaths in Uganda and widespread chronic illnesses are attributed to urinary tract / bladder problems. Early diagnosis will save resources now devoted to investigate, treat to save organ function, and reduce hypertension. A prototype device at the University of British Columbia uses light to measure hemoglobin and oxygen levels through the skin as the bladder empties, revealing significant problems in real time. Novel disruptive optical technology now identifies when the bladder is significantly diseased or compromised.

Active pair study is implemented by the Institute of Human Virology Nigeria. It involves behavioral interventions in diet and physical activity, using education, motivation and tracking programs, to reduce the burden of obesity and physical inactivity on the health care system, as well as decrease obesity related deaths. Follow Sally Akarolo-Anthony on Twitter @sally_anthony"